HIV Resistance Sensor

Untreated HIV Infection is Fatal

The Human Immunodeficiency Virus (HIV) has spread worldwide since 1980 and has reportedly killed nearly 40 million people as the infection progresses to its final stage, AIDS. HIV targets certain cells of our immune system (C4-type T-helper cells), weakening the body’s defense mechanisms, making those infected highly susceptible to infections. Early symptoms resemble the flu, but later stages often result in significant weight loss, night sweats, diarrhea, and immune deficiencies like pneumonia, yeast infections, or tuberculosis.

With the development of effective medications that prevent viral replication, alleviate symptoms, or boost immune strength, an HIV infection detected early is treatable, and the death toll is declining. However, it remains incurable. In 2014 alone, more than 1.2 million people died due to undiagnosed or late-diagnosed HIV infection, especially in countries with poor medical infrastructure.

HIV is transmitted through contact with bodily fluids, such as blood, which can allow the virus to enter the body through small wounds. Most infections occur during unprotected sex, but drug users frequently contract the virus through needle sticks, such as syringes previously used by infected individuals.

Our Genes Influence the Risk of Infection

Although there is no foolproof protection against HIV, not everyone is equally likely to become infected after exposure to the virus.

Depending on variations in a specific gene, the risk of infection may be significantly reduced or increased. Analyzing this gene allows us to categorize your genetic type into one of the aforementioned risk groups.

How Does Our HIV Resistance Sensor Work?

With our HIV Resistance Sensor, our laboratory examines the submitted sample for the CCR5 gene, which is associated with the risk of HIV infection. At the same time, we analyze approximately 40 gene variants for the effectiveness of 30 medications.

This genetic test helps determine how likely an HIV infection is and how a potential treatment should be carried out.

We summarize the analysis results in a clear written report that outlines your individual risk of infection on a scale and provides a table of effective medications for treatment.

In this way, our HIV Resistance Sensor can identify your individual risk for HIV infection and provide important treatment guidance.